To help enterprise decision-makers navigate this complex vendor landscape, we have evaluated the leading AI software development companies in the US. Our assessment focuses on innovation, industry impact, technical expertise, and proven results in delivering scalable AI solutions.
Top AI Software Development Companies in the US
| Rank | Company | Headquarters | Specialties |
|---|---|---|---|
| 1 | 247 Labs | Toronto / US-Focused | Custom AI, Machine Learning, AI Agents, Enterprise Automation |
| 2 | LeewayHertz | San Francisco, CA | Generative AI, LLMs, Enterprise AI Solutions |
| 3 | C3 AI | Redwood City, CA | Enterprise AI Applications, Predictive Analytics |
| 4 | RTS Labs | Richmond, VA | Data Science, AI Strategy, Custom Software |
| 5 | EliseAI | New York, NY | Conversational AI, Real Estate Automation |
| 6 | Markovate | San Francisco, CA | AI/ML, Web & Mobile App Development |
| 7 | AIBrain | Palo Alto, CA | Cognitive AI, Human-Centric AI Robotics |
| 8 | OpenXcell | Las Vegas, NV | AI Solutions, Software Engineering |
| 9 | SoluLab | Los Angeles, CA | AI, Blockchain, Digital Transformation |
| 10 | 10Pearls | Vienna, VA | AI Product Development, Digital Engineering |
1. 247 Labs
Website: 247labs.com
Headquarters: Toronto, ON (Serving US & Global Markets)
Key Awards: DesignRush Top AI Development Company, Top App Firms AI Development, Clutch Global Champion
247 Labs stands at the forefront of AI innovation, specializing in custom software development and intelligent automation. We empower businesses to solve complex challenges through data-driven insights and AI-powered systems. Our commitment to excellence is reflected in our recent DesignRush award for top mobile and AI development, as well as our recognition by Top App Firms as a leader in Artificial Intelligence development.
We don’t just build software; we build solutions that improve lives. Our AI expertise spans across industries, from healthcare diagnostic tools to intelligent chatbots for global enterprises.
- Expertise: Custom AI/ML, Business Process Automation with AI Agents, and Enterprise Mobility.
- Notable AI Case Study: An AI-Driven Platform for Accurate Detection of Oral Health Issues and Image Recognition for Indigenous Education.
2. LeewayHertz
Website: leewayhertz.com
Headquarters: San Francisco, CA
LeewayHertz is a prominent player in the US AI space, known for its deep expertise in Generative AI and Large Language Models (LLMs). They provide comprehensive AI consulting and development services, helping enterprises integrate advanced AI into their existing workflows to drive efficiency.
3. C3 AI
Website: c3.ai
Headquarters: Redwood City, CA
C3 AI is a global leader in enterprise AI software. They offer a robust platform for developing, deploying, and operating large-scale AI, predictive analytics, and IoT applications. Their solutions are widely used in sectors like energy, manufacturing, and financial services.
4. RTS Labs
Website: rtslabs.com
Headquarters: Richmond, VA
RTS Labs specializes in helping businesses leverage data to make better decisions. Their AI and data science teams focus on creating custom solutions that provide actionable insights, helping clients stay ahead of the curve in a data-centric world.
5. EliseAI
Website: eliseai.com
Headquarters: New York, NY
EliseAI is a pioneer in conversational AI, specifically tailored for the real estate industry. Their AI-driven platform automates customer interactions, from lead management to resident support, significantly improving operational efficiency for property managers.
6. Markovate
Website: markovate.com
Headquarters: San Francisco, CA
Markovate focuses on building AI-powered mobile and web applications. They combine technical prowess with a deep understanding of user experience to deliver products that are not only intelligent but also highly engaging.
7. AIBrain
Website: aibrain.com
Headquarters: Palo Alto, CA
AIBrain is dedicated to the development of “human-like” AI. Their research in cognitive AI and its application in robotics and augmented reality sets them apart as a highly innovative firm focused on the future of human-AI interaction.
8. OpenXcell
Website: openxcell.com
Headquarters: Las Vegas, NV
OpenXcell provides a wide range of software development services, with a strong emphasis on AI and machine learning. They help businesses transform their digital presence through custom-built AI solutions that address specific business needs.
9. SoluLab
Website: solulab.com
Headquarters: Los Angeles, CA
SoluLab is a digital transformation partner that excels in emerging technologies, including AI and blockchain. They offer end-to-end AI development services, from strategy and consulting to deployment and maintenance.
10. 10Pearls
Website: 10pearls.com
Headquarters: Vienna, VA
10Pearls is a global digital engineering firm that helps businesses accelerate their AI initiatives. They focus on delivering scalable and secure AI products that drive business value across various industries, including healthcare and fintech.
Conclusion
Choosing the right AI development partner is a critical decision that can determine the success of your digital transformation journey. The companies listed above represent the best in the US, each bringing unique strengths to the table. At 247 Labs, we are proud to lead this list, driven by our mission to deliver innovative, ethically sound, and high-impact AI solutions.
Ready to transform your business with AI?
Schedule a discovery call with our experts today to explore how 247 Labs can help you stay ahead of the technology curve.


